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Text File  |  1987-11-10  |  554b  |  14 lines
  1.          IN PATIENTS WITH RENAL IMPAIRMENT, MEZLOCILLIN DOSAGE SHOULD
  2.          BE CAREFULLY ADJUSTED TO AVOID TOXICITY (ALLERGIC
  3.          INTERSTITIAL NEPHRITIS, SEIZURES, AND COAGULOPATHY).
  4.  
  5.          SOME CLINICIANS RECOMMEND THAT THE DOSAGE REGIMEN BE
  6.          ADJUSTED BASED ON THE PATIENT'S CREATININE CLEARANCE:
  7.  
  8.                 CREATININE
  9.                  CLEARANCE      MAXIMUM RECOMMENDED DOSAGE
  10.                 (ML/MINUTE)
  11.  
  12.                   10-30             3g Q 8 hours
  13.                    <10              1.5 to 2g Q 8 hours
  14.